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Evaluation of Pharmacokinetics and Dose Proportionality of Diazepam After Intranasal Administration of NRL‐1 to Healthy Volunteers

NRL‐1 is a novel intranasal formulation of diazepam that is being evaluated as rescue medication in patients with epilepsy who experience bouts of increased seizure activity despite stable regimens of antiepileptic drugs. This phase 1, open‐label, randomized, crossover study in healthy adult volunte...

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Detalles Bibliográficos
Autores principales: Tanimoto, Sarina, Pesco Koplowitz, Luana, Lowenthal, Richard E., Koplowitz, Barry, Rabinowicz, Adrian L., Carrazana, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497078/
https://www.ncbi.nlm.nih.gov/pubmed/31916704
http://dx.doi.org/10.1002/cpdd.767