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Fluorophore‐Labeled Cyclic Nucleotides as Potent Agonists of Cyclic Nucleotide‐Regulated Ion Channels

High‐affinity fluorescent derivatives of cyclic adenosine and guanosine monophosphate are powerful tools for investigating their natural targets. Cyclic nucleotide‐regulated ion channels belong to these targets and are vital for many signal transduction processes, such as vision and olfaction. The r...

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Detalles Bibliográficos
Autores principales: Lelle, Marco, Otte, Maik, Bonus, Michele, Gohlke, Holger, Benndorf, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497086/
https://www.ncbi.nlm.nih.gov/pubmed/32227403
http://dx.doi.org/10.1002/cbic.202000116