Cargando…

Mechanosensitive regulation of stanniocalcin‐1 by zyxin and actin‐myosin in human mesenchymal stromal cells

Stanniocalcin‐1 (STC1) secreted by mesenchymal stromal cells (MSCs) has anti‐inflammatory functions, reduces apoptosis, and aids in angiogenesis, both in vitro and in vivo. However, little is known about the molecular mechanisms of its regulation. Here, we show that STC1 secretion is increased only...

Descripción completa

Detalles Bibliográficos
Autores principales: Zonderland, Jip, Gomes, David B., Pallada, Yves, Moldero, Ivan L., Camarero‐Espinosa, Sandra, Moroni, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497098/
https://www.ncbi.nlm.nih.gov/pubmed/32379914
http://dx.doi.org/10.1002/stem.3198