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Bidirectional regulation of distinct memory domains by α5-subunit-containing GABA(A) receptors in CA1 pyramidal neurons

Reduction in the expression or function of α5-subunit-containing GABA(A) receptors (α5GABA(A)Rs) leads to improvement in several hippocampus-dependent memory domains. However, studies thus far mostly lack anatomical specificity in terms of neuronal circuits and populations. We demonstrate that mice...

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Detalles Bibliográficos
Autores principales: Engin, Elif, Sigal, Maksim, Benke, Dietmar, Zeller, Anja, Rudolph, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497110/
https://www.ncbi.nlm.nih.gov/pubmed/32934095
http://dx.doi.org/10.1101/lm.052084.120