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Identification of the minimum region of Bordetella pertussis Vag8 required for interaction with C1 inhibitor

An autotransporter of Bordetella pertussis, virulence‐associated gene 8 (Vag8), binds and inactivates the complement regulator, C1 inhibitor (C1‐Inh), and plays a role in evasion of the complement system. However, the molecular interaction between Vag8 and C1‐Inh remains unclear. Here, we localized...

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Detalles Bibliográficos
Autores principales: Onoda, Naoki, Hiramatsu, Yukihiro, Teruya, Shihono, Suzuki, Koichiro, Horiguchi, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497153/
https://www.ncbi.nlm.nih.gov/pubmed/32396237
http://dx.doi.org/10.1111/1348-0421.12799