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Bioactive indanes: insight into the bioactivity of indane dimers related to the lead anti-inflammatory molecule PH46A

OBJECTIVES: PH46A (1) demonstrates significant anti-inflammatory activity in phenotypic models but its mechanism and site of action have been elusive. Current study focused on the bioactivity of PH46 (2) and related novel indane dimers (6-10) to investigate the impact of changes in substitution and...

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Detalles Bibliográficos
Autores principales: Chan, Kit, Frankish, Neil, Zhang, Tao, Ece, Abdulilah, Cannon, Aoife, O'Sullivan, Jacintha, Sheridan, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497186/
https://www.ncbi.nlm.nih.gov/pubmed/32301120
http://dx.doi.org/10.1111/jphp.13269