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Bioactive indanes: insight into the bioactivity of indane dimers related to the lead anti-inflammatory molecule PH46A
OBJECTIVES: PH46A (1) demonstrates significant anti-inflammatory activity in phenotypic models but its mechanism and site of action have been elusive. Current study focused on the bioactivity of PH46 (2) and related novel indane dimers (6-10) to investigate the impact of changes in substitution and...
Autores principales: | Chan, Kit, Frankish, Neil, Zhang, Tao, Ece, Abdulilah, Cannon, Aoife, O'Sullivan, Jacintha, Sheridan, Helen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497186/ https://www.ncbi.nlm.nih.gov/pubmed/32301120 http://dx.doi.org/10.1111/jphp.13269 |
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