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Total Syntheses of (−)‐Minovincine and (−)‐Aspidofractinine through a Sequence of Cascade Reactions

We report 8‐step syntheses of (−)‐minovincine and (−)‐aspidofractinine using easily available and inexpensive reagents and catalyst. A key element of the strategy was the utilization of a sequence of cascade reactions to rapidly construct the penta‐ and hexacyclic frameworks. These cascade transform...

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Detalles Bibliográficos
Autores principales: Varga, Szilárd, Angyal, Péter, Martin, Gábor, Egyed, Orsolya, Holczbauer, Tamás, Soós, Tibor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497198/
https://www.ncbi.nlm.nih.gov/pubmed/32351014
http://dx.doi.org/10.1002/anie.202004769