Cargando…

Total Syntheses of (−)‐Minovincine and (−)‐Aspidofractinine through a Sequence of Cascade Reactions

We report 8‐step syntheses of (−)‐minovincine and (−)‐aspidofractinine using easily available and inexpensive reagents and catalyst. A key element of the strategy was the utilization of a sequence of cascade reactions to rapidly construct the penta‐ and hexacyclic frameworks. These cascade transform...

Descripción completa

Detalles Bibliográficos
Autores principales:	Varga, Szilárd, Angyal, Péter, Martin, Gábor, Egyed, Orsolya, Holczbauer, Tamás, Soós, Tibor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497198/ https://www.ncbi.nlm.nih.gov/pubmed/32351014 http://dx.doi.org/10.1002/anie.202004769

Ejemplares similares

Total Syntheses of Dihydroindole Aspidosperma Alkaloids: Reductive Interrupted Fischer Indolization Followed by Redox Diversification
por: Martin, Gábor, et al.
Publicado: (2020)

Total Synthesis of (±)-Aspidospermidine, (±)-Aspidofractinine, (±)-Limaspermidine, and (±)-Vincadifformine via a Cascade and Common Intermediate Strategy
por: Cain, David L., et al.
Publicado: (2022)

Syntheses of 2- and 3-Substituted Morpholine Congeners via Ring Opening of 2-Tosyl-1,2-Oxazetidine
por: Kőnig, Bálint, et al.
Publicado: (2023)

Intertwining Olefin Thianthrenation with Kornblum/Ganem Oxidations: Ene‐type Oxidation to Furnish α,β‐Unsaturated Carbonyls
por: Angyal, Péter, et al.
Publicado: (2022)

Enantioselective construction of cis-hydroindole scaffolds via an asymmetric inverse-electron-demand Diels–Alder reaction: application to the formal total synthesis of (+)-minovincine
por: Zhang, Fangqing, et al.
Publicado: (2022)

Strain and Complexity, Passerini and Ugi Reactions of Four‐Membered Heterocycles and Further Elaboration of TOSMIC Product
por: Sztanó, Gábor, et al.
Publicado: (2023)

A photoresponsive palladium complex of an azopyridyl-triazole ligand: light-controlled solubility drives catalytic activity in the Suzuki coupling reaction
por: Kunfi, Attila, et al.
Publicado: (2021)

Syntheses and Reactions of Pyrroline, Piperidine Nitroxide Phosphonates
por: Isbera, Mostafa, et al.
Publicado: (2020)

Diastereo- and Enantioselective Syntheses of Trisubstituted Benzopyrans by Cascade Reactions Catalyzed by Monomeric and Polymeric Recoverable Bifunctional Thioureas and Squaramides
por: Andrés, José M., et al.
Publicado: (2018)

Echinococcus multilocularis: An Emerging Pathogen in Hungary and Central Eastern Europe?
por: Sréter, Tamás, et al.
Publicado: (2003)

Unsymmetrical Thienopentalenes: Synthesis, Optoelectronic Properties, and (Anti)aromaticity Analysis
por: Gazdag, Tamás, et al.
Publicado: (2022)

Microbiologically-Synthesized Nanoparticles and Their Role in Silencing the Biofilm Signaling Cascade
por: Lahiri, Dibyajit, et al.
Publicado: (2021)

Direct Assembly of Prenylated Heteroarenes through a Cascade Minisci Reaction/Dehydration Sequence
por: Tan, Dong‐Hang, et al.
Publicado: (2016)

Crystal structure of diaquatris(1-ethyl-1H-imidazole-κN (3))(sulfato-κO)nickel(II)
por: Holczbauer, Tamas, et al.
Publicado: (2016)

A cyanide-catalyzed imino-Stetter reaction enables the concise total syntheses of rucaparib
por: Park, Jinjae, et al.
Publicado: (2022)

Enantioseparation of P-Stereogenic Secondary Phosphine Oxides and Their Stereospecific Transformation to Various Tertiary Phosphine Oxides and a Thiophosphinate
por: Varga, Bence, et al.
Publicado: (2021)

Enantioseparation of P-Stereogenic 1-Adamantyl Arylthiophosphonates and Their Stereospecific Transformation to 1-Adamantyl Aryl-H-phosphinates
por: Varga, Bence, et al.
Publicado: (2023)

Systems-Level Feedbacks of NRF2 Controlling Autophagy upon Oxidative Stress Response
por: Kapuy, Orsolya, et al.
Publicado: (2018)

Concise Access to the Skeleton of Protoilludane Sesquiterpenes through a Photochemical Reaction Cascade: Total Synthesis of Atlanticone C
por: Zech, Andreas, et al.
Publicado: (2019)

Total Syntheses of (+)- and (−)-Peribysin E
por: Angeles, Angie R., et al.
Publicado: (2008)

Machine learning framework to segment sarcomeric structures in SMLM data
por: Varga, Dániel, et al.
Publicado: (2023)

Meroterpenoid Synthesis via Sequential Polyketide Aromatization and Radical Anion Cascade Triene Cyclization: Biomimetic Total Syntheses of Austalide Natural Products
por: Ma, Tsz-Kan, et al.
Publicado: (2019)

Asymmetric Total Synthesis of (+)-21-epi-Eburnamonine Via a Photocatalytic Radical Cascade Reaction
por: Huang, Yuan, et al.
Publicado: (2020)

Dichloridobis(2-methoxydibenzo[c,e][1,2]oxaphosphorine-κP)platinum(II) trichloromethane solvate
por: Holczbauer, Tamás, et al.
Publicado: (2009)

Single-Cell Sequencing: Biological Insight and Potential Clinical Implications in Pediatric Leukemia
por: Alpár, Donát, et al.
Publicado: (2021)

A review of the total syntheses of triptolide
por: Zhang, Xiang, et al.
Publicado: (2019)

Total syntheses of shizukaols A and E
por: Wu, Jian-Li, et al.
Publicado: (2018)

Total syntheses of strained polycyclic terpenes
por: Chesnokov, Gleb A., et al.
Publicado: (2022)

Total Syntheses of (+)-Ineleganolide and (−)-Sinulochmodin C
por: Tuccinardi, Joseph P., et al.
Publicado: (2022)

Total Syntheses of Nominal and Actual Prorocentin
por: Zachmann, Raphael J., et al.
Publicado: (2023)

Total Syntheses of Phleghenrines A and C
por: Cai, Xinpei, et al.
Publicado: (2023)

Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints
por: Angyal, Adrienn, et al.
Publicado: (2010)

The binary cascade: nucleon nuclear reactions
por: Folger, G, et al.
Publicado: (2004)

Theoretical investigation of Banert cascade reaction
por: Bhattacharyya, S., et al.
Publicado: (2018)

Structure–Property Relationships in Unsymmetric Bis(antiaromatics): Who Wins the Battle between Pentalene and Benzocyclobutadiene?†
por: Mayer, Péter J., et al.
Publicado: (2020)

Cascade polymerizations: recent developments in the formation of polymer repeat units by cascade reactions
por: Peterson, Gregory I., et al.
Publicado: (2020)

A meiotic gene regulatory cascade driven by alternative fates for newly synthesized transcripts
por: Cremona, Nicole, et al.
Publicado: (2011)

Enantioselective Total Syntheses of Preussomerins: Control of Spiroacetal Stereogenicity by Photochemical Reaction of a Naphthoquinone through 1,6‐Hydrogen Atom Transfer
por: Ando, Yoshio, et al.
Publicado: (2022)

Kinetic Role of Reactive Intermediates in Controlling the Formation of Chlorine Dioxide in the Hypochlorous Acid–Chlorite Ion Reaction
por: Angyal, Dávid, et al.
Publicado: (2023)

Total Syntheses of Pladienolide-Derived Spliceosome Modulators
por: Sim, Jaehoon, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_75r2ho3f90til84ppdhr23per7