Mesenchymal stromal cells induce regulatory T cells via epigenetic conversion of human conventional CD4 T cells in vitro

Regulatory T cells (Treg) play a critical role in immune tolerance. The scarcity of Treg therapy clinical trials in humans has been largely due to the difficulty in obtaining sufficient Treg numbers. We performed a preclinical investigation on the potential of mesenchymal stromal cells (MSCs) to exp...

Descripción completa

Detalles Bibliográficos
Autores principales: Azevedo, Rita I., Minskaia, Ekaterina, Fernandes‐Platzgummer, Ana, Vieira, Ana I. S., da Silva, Cláudia L., Cabral, Joaquim M. S., Lacerda, João F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Translational and Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497276/
https://www.ncbi.nlm.nih.gov/pubmed/32352186
http://dx.doi.org/10.1002/stem.3185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497276/
https://www.ncbi.nlm.nih.gov/pubmed/32352186
http://dx.doi.org/10.1002/stem.3185

Ejemplares similares