Design, synthesis, and biological evaluation of novel arylcarboxamide derivatives as anti-tubercular agents

Our group has previously reported several indolecarboxamides exhibiting potent antitubercular activity. Herein, we rationally designed several arylcarboxamides based on our previously reported homology model and the recently published crystal structure of the mycobacterial membrane protein large 3 (...

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Detalles Bibliográficos
Autores principales: Alsayed, Shahinda S. R., Lun, Shichun, Luna, Giuseppe, Beh, Chau Chun, Payne, Alan D., Foster, Neil, Bishai, William R., Gunosewoyo, Hendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497412/
https://www.ncbi.nlm.nih.gov/pubmed/33014349
http://dx.doi.org/10.1039/c9ra10663d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497412/
https://www.ncbi.nlm.nih.gov/pubmed/33014349
http://dx.doi.org/10.1039/c9ra10663d

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