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Design, synthesis, and biological evaluation of novel arylcarboxamide derivatives as anti-tubercular agents
Our group has previously reported several indolecarboxamides exhibiting potent antitubercular activity. Herein, we rationally designed several arylcarboxamides based on our previously reported homology model and the recently published crystal structure of the mycobacterial membrane protein large 3 (...
Autores principales: | Alsayed, Shahinda S. R., Lun, Shichun, Luna, Giuseppe, Beh, Chau Chun, Payne, Alan D., Foster, Neil, Bishai, William R., Gunosewoyo, Hendra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497412/ https://www.ncbi.nlm.nih.gov/pubmed/33014349 http://dx.doi.org/10.1039/c9ra10663d |
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