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Maternal low-dose aspartame and stevia consumption with an obesogenic diet alters metabolism, gut microbiota and mesolimbic reward system in rat dams and their offspring

OBJECTIVE: We examined the impact of maternal low-dose aspartame and stevia consumption on adiposity, glucose tolerance, gut microbiota and mesolimbic pathway in obese dams and their offspring. DESIGN: Following obesity induction, female Sprague-Dawley rats were allocated during pregnancy and lactat...

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Detalles Bibliográficos
Autores principales: Nettleton, Jodi E, Cho, Nicole A, Klancic, Teja, Nicolucci, Alissa C, Shearer, Jane, Borgland, Stephanie L, Johnston, Leah A, Ramay, Hena R, Noye Tuplin, Erin, Chleilat, Faye, Thomson, Carolyn, Mayengbam, Shyamchand, McCoy, Kathy D, Reimer, Raylene A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497576/
https://www.ncbi.nlm.nih.gov/pubmed/31996393
http://dx.doi.org/10.1136/gutjnl-2018-317505