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The transition from acute to chronic pain: dynamic epigenetic reprogramming of the mouse prefrontal cortex up to 1 year after nerve injury

Chronic pain is associated with persistent structural and functional changes throughout the neuroaxis, including in the prefrontal cortex (PFC). The PFC is important in the integration of sensory, cognitive, and emotional information and in conditioned pain modulation. We previously reported widespr...

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Detalles Bibliográficos
Autores principales: Topham, Lucas, Gregoire, Stephanie, Kang, HyungMo, Salmon-Divon, Mali, Lax, Elad, Millecamps, Magali, Szyf, Moshe, Stone, Laura S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497614/
https://www.ncbi.nlm.nih.gov/pubmed/32427748
http://dx.doi.org/10.1097/j.pain.0000000000001917