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Machine-Vision-Enabled Salt Dissolution Analysis
[Image: see text] Salt formation is a well-established method to increase the solubility of ionizable drug candidates. However, possible conversion of salt to its original form of free acid or base—disproportionation—can have a drastic effect on the solubility and consequently the bioavailability of...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical
Society
2020
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497625/ https://www.ncbi.nlm.nih.gov/pubmed/32544319 http://dx.doi.org/10.1021/acs.analchem.0c01068 |