Cargando…

Kendomycin Cytotoxicity against Bacterial, Fungal, and Mammalian Cells Is Due to Cation Chelation

[Image: see text] Kendomycin is a small-molecule natural product that has gained significant attention due to reported cytotoxicity against pathogenic bacteria and fungi as well as a number of cancer cell lines. Despite significant biomedical interest and attempts to reveal its mechanism of action,...

Descripción completa

Detalles Bibliográficos
Autores principales: Tranter, Dale, Filipuzzi, Ireos, Lochmann, Thomas, Knapp, Britta, Kellosalo, Juho, Estoppey, David, Pistorius, Dominik, Meissner, Axel, Paavilainen, Ville O., Hoepfner, Dominic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497661/
https://www.ncbi.nlm.nih.gov/pubmed/32182062
http://dx.doi.org/10.1021/acs.jnatprod.9b00826