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Binding Site Interactions of Modulators of Breast Cancer Resistance Protein, Multidrug Resistance-Associated Protein 2, and P-Glycoprotein Activity

[Image: see text] ATP-binding cassette (ABC)-transporters protect tissues by pumping their substrates out of the cells in many physiological barriers, such as the blood–brain barrier, intestine, liver, and kidney. These substrates include various endogenous metabolites, but, in addition, ABC transpo...

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Detalles Bibliográficos
Autores principales: Deng, Feng, Ghemtio, Leo, Grazhdankin, Evgeni, Wipf, Peter, Xhaard, Henri, Kidron, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497665/
https://www.ncbi.nlm.nih.gov/pubmed/32496785
http://dx.doi.org/10.1021/acs.molpharmaceut.0c00155