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Identification of candidate mediators of chemoresponse in breast cancer through therapy-driven selection of somatic variants

PURPOSE: More than a third of primary breast cancer patients are treated with cytotoxic chemotherapy, typically without guidance from predictive markers. Increased use of neoadjuvant chemotherapy provides opportunities for identification of molecules associated with treatment response, by comparing...

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Detalles Bibliográficos
Autores principales: Al Amri, Waleed S., Baxter, Diana E., Hanby, Andrew M., Stead, Lucy F., Verghese, Eldo T., Thorne, James L., Hughes, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497675/
https://www.ncbi.nlm.nih.gov/pubmed/32734521
http://dx.doi.org/10.1007/s10549-020-05836-7