Structure-based design, synthesis, and evaluation of the biological activity of novel phosphoroorganic small molecule IAP antagonists

One of the strategies employed by novel anticancer therapies is to put the process of apoptosis back on track by blocking the interaction between inhibitor of apoptosis proteins (IAPs) and caspases. The activity of caspases is modulated by the caspases themselves in a caspase/procaspase proteolytic...

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Detalles Bibliográficos
Autores principales: Łupicka-Słowik, Agnieszka, Psurski, Mateusz, Grzywa, Renata, Cuprych, Monika, Ciekot, Jarosław, Goldeman, Waldemar, Wojaczyńska, Elżbieta, Wojaczyński, Jacek, Oleksyszyn, Józef, Sieńczyk, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Preclinical Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497679/
https://www.ncbi.nlm.nih.gov/pubmed/32270379
http://dx.doi.org/10.1007/s10637-020-00923-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497679/
https://www.ncbi.nlm.nih.gov/pubmed/32270379
http://dx.doi.org/10.1007/s10637-020-00923-4

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