Phase I study of metformin in combination with carboplatin/paclitaxel chemotherapy in patients with advanced epithelial ovarian cancer

Background Metformin use is associated with reduced cancer risk in epidemiological studies and has preclinical anti-cancer activity in ovarian cancer models. The primary objective of this phase I study was to determine the recommended phase II dose (RP2D) of metformin in combination with carboplatin...

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Detalles Bibliográficos
Autores principales: Broekman, K. Esther, Hof, Marieke A. J., Touw, Daan J., Gietema, Jourik A., Nijman, Hans W., Lefrandt, Joop D., Reyners, An K. L., Jalving, Mathilde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Phase I Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497683/
https://www.ncbi.nlm.nih.gov/pubmed/32146550
http://dx.doi.org/10.1007/s10637-020-00920-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497683/
https://www.ncbi.nlm.nih.gov/pubmed/32146550
http://dx.doi.org/10.1007/s10637-020-00920-7

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