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Intratumoral submicron particle docetaxel inhibits syngeneic Renca renal cancer growth and increases CD4+, CD8+, and Treg levels in peripheral blood

Administration of chemotherapeutics as direct injections into tumors offers increased anti-tumor activity and reduced systemic toxicity. In this study, the Renca syngeneic murine xenograft model of renal cancer was used to evaluate the effects of intratumoral (IT) submicron particle docetaxel (NanoD...

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Detalles Bibliográficos
Autores principales: Maulhardt, Holly A., Marin, Alyson M., diZerega, Gere S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497695/
https://www.ncbi.nlm.nih.gov/pubmed/32198648
http://dx.doi.org/10.1007/s10637-020-00922-5