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Superoxide and Non-ionotropic Signaling in Neuronal Excitotoxicity
Excitotoxicity is classically attributed to Ca(2+) influx through NMDA receptors (NMDAr), leading to production of nitric oxide by neuronal nitric oxide synthase and superoxide by mitochondria, which react to form highly cytotoxic peroxynitrite. More recent observations warrant revision of the class...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497801/ https://www.ncbi.nlm.nih.gov/pubmed/33013314 http://dx.doi.org/10.3389/fnins.2020.00861 |