Targeting DNA Methylation Depletes Uterine Leiomyoma Stem Cell–enriched Population by Stimulating Their Differentiation

Uterine leiomyoma (LM) is the most common tumor in women and can cause severe morbidity. Leiomyoma growth requires the maintenance and proliferation of a stem cell population. Dysregulated deoxyribonucleic acid (DNA) methylation has been reported in LM, but its role in LM stem cell regulation remain...

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Detalles Bibliográficos
Autores principales: Liu, Shimeng, Yin, Ping, Xu, Jingting, Dotts, Ariel J, Kujawa, Stacy A, Coon V, John S, Zhao, Hong, Shilatifard, Ali, Dai, Yang, Bulun, Serdar E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497820/
https://www.ncbi.nlm.nih.gov/pubmed/32812024
http://dx.doi.org/10.1210/endocr/bqaa143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497820/
https://www.ncbi.nlm.nih.gov/pubmed/32812024
http://dx.doi.org/10.1210/endocr/bqaa143

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