Cargando…

A complement component C1q-mediated mechanism of antibody-dependent enhancement of Ebola virus infection

Besides the common Fc receptor (FcR)-mediated mechanism of antibody-dependent enhancement (ADE), Ebola virus (EBOV) is known to utilize the complement component C1q for ADE of infection. This mechanism is FcR-independent and mediated by cross-linking of virus-antibody-C1q complexes to cell surface C...

Descripción completa

Detalles Bibliográficos
Autores principales: Furuyama, Wakako, Nanbo, Asuka, Maruyama, Junki, Marzi, Andrea, Takada, Ayato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497997/
https://www.ncbi.nlm.nih.gov/pubmed/32886656
http://dx.doi.org/10.1371/journal.pntd.0008602