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Partitioning stable and unstable expression level variation in cell populations: A theoretical framework and its application to the T cell receptor
Phenotypic variation in the copy number of gene products expressed by cells or tissues has been the focus of intense investigation. To what extent the observed differences in cellular expression levels are persistent or transient is an intriguing question. Here, we develop a quantitative framework t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498022/ https://www.ncbi.nlm.nih.gov/pubmed/32841238 http://dx.doi.org/10.1371/journal.pcbi.1007910 |