Human cytomegalovirus evades ZAP detection by suppressing CpG dinucleotides in the major immediate early 1 gene

The genomes of RNA and small DNA viruses of vertebrates display significant suppression of CpG dinucleotide frequencies. Artificially increasing dinucleotide frequencies results in substantial attenuation of virus replication, suggesting that these compositional changes may facilitate recognition of...

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Detalles Bibliográficos
Autores principales: Lin, Yao-Tang, Chiweshe, Stephen, McCormick, Dominique, Raper, Anna, Wickenhagen, Arthur, DeFillipis, Victor, Gaunt, Eleanor, Simmonds, Peter, Wilson, Sam J., Grey, Finn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498042/
https://www.ncbi.nlm.nih.gov/pubmed/32886716
http://dx.doi.org/10.1371/journal.ppat.1008844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498042/
https://www.ncbi.nlm.nih.gov/pubmed/32886716
http://dx.doi.org/10.1371/journal.ppat.1008844

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