Isolation of antigen-specific, disulphide-rich knob domain peptides from bovine antibodies

As a novel alternative to established surface display or combinatorial chemistry approaches for the discovery of therapeutic peptides, we present a method for the isolation of small, cysteine-rich domains from bovine antibody ultralong complementarity-determining regions (CDRs). We show for the firs...

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Detalles Bibliográficos
Autores principales: Macpherson, Alex, Scott-Tucker, Anthony, Spiliotopoulos, Anastasios, Simpson, Catherine, Staniforth, Justin, Hold, Adam, Snowden, James, Manning, Leah, van den Elsen, Jean, Lawson, Alastair D. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Methods and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498065/
https://www.ncbi.nlm.nih.gov/pubmed/32886672
http://dx.doi.org/10.1371/journal.pbio.3000821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498065/
https://www.ncbi.nlm.nih.gov/pubmed/32886672
http://dx.doi.org/10.1371/journal.pbio.3000821

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