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Isolation of antigen-specific, disulphide-rich knob domain peptides from bovine antibodies
As a novel alternative to established surface display or combinatorial chemistry approaches for the discovery of therapeutic peptides, we present a method for the isolation of small, cysteine-rich domains from bovine antibody ultralong complementarity-determining regions (CDRs). We show for the firs...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498065/ https://www.ncbi.nlm.nih.gov/pubmed/32886672 http://dx.doi.org/10.1371/journal.pbio.3000821 |