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Cross-utilisation of template RNAs by alphavirus replicases

Most alphaviruses (family Togaviridae) including Sindbis virus (SINV) and other human pathogens, are transmitted by arthropods. The first open reading frame in their positive strand RNA genome encodes for the non-structural polyprotein, a precursor to four separate subunits of the replicase. The rep...

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Detalles Bibliográficos
Autores principales: Lello, Laura Sandra, Utt, Age, Bartholomeeusen, Koen, Wang, Sainan, Rausalu, Kai, Kendall, Catherine, Coppens, Sandra, Fragkoudis, Rennos, Tuplin, Andrew, Alphey, Luke, Ariën, Kevin K., Merits, Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498090/
https://www.ncbi.nlm.nih.gov/pubmed/32886709
http://dx.doi.org/10.1371/journal.ppat.1008825