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Regio- and Diastereoselective Synthesis of 2-Arylazetidines: Quantum Chemical Explanation of Baldwin’s Rules for the Ring-Formation Reactions of Oxiranes†

[Image: see text] A general, scalable two-step regio- and diastereoselective method has been described for the synthesis of versatile alkaloid-type azetidines from simple building blocks with excellent overall yields. In the kinetically controlled reaction, only the formation of the strained four-me...

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Detalles Bibliográficos
Autores principales: Kovács, Ervin, Faigl, Ferenc, Mucsi, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498157/
https://www.ncbi.nlm.nih.gov/pubmed/32786621
http://dx.doi.org/10.1021/acs.joc.0c01310