Structure–Activity Relationship Studies of α-Ketoamides as Inhibitors of the Phospholipase A and Acyltransferase Enzyme Family

[Image: see text] The phospholipase A and acyltransferase (PLAAT) family of cysteine hydrolases consists of five members, which are involved in the Ca(2+)-independent production of N-acylphosphatidylethanolamines (NAPEs). NAPEs are lipid precursors for bioactive N-acylethanolamines (NAEs) that are i...

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Detalles Bibliográficos
Autores principales: Zhou, Juan, Mock, Elliot D., Al Ayed, Karol, Di, Xinyu, Kantae, Vasudev, Burggraaff, Lindsey, Stevens, Anna F., Martella, Andrea, Mohr, Florian, Jiang, Ming, van der Wel, Tom, Wendel, Tiemen J., Ofman, Tim P., Tran, Yvonne, de Koster, Nicky, van Westen, Gerard J.P., Hankemeier, Thomas, van der Stelt, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498158/
https://www.ncbi.nlm.nih.gov/pubmed/32787138
http://dx.doi.org/10.1021/acs.jmedchem.0c00522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498158/
https://www.ncbi.nlm.nih.gov/pubmed/32787138
http://dx.doi.org/10.1021/acs.jmedchem.0c00522

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