Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endoderm gene regulatory network

Lineage specification is governed by gene regulatory networks (GRNs) that integrate the activity of signaling effectors and transcription factors (TFs) on enhancers. Sox17 is a key transcriptional regulator of definitive endoderm development, and yet, its genomic targets remain largely uncharacteriz...

Descripción completa

Detalles Bibliográficos
Autores principales: Mukherjee, Shreyasi, Chaturvedi, Praneet, Rankin, Scott A, Fish, Margaret B, Wlizla, Marcin, Paraiso, Kitt D, MacDonald, Melissa, Chen, Xiaoting, Weirauch, Matthew T, Blitz, Ira L, Cho, Ken WY, Zorn, Aaron M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498262/
https://www.ncbi.nlm.nih.gov/pubmed/32894225
http://dx.doi.org/10.7554/eLife.58029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498262/
https://www.ncbi.nlm.nih.gov/pubmed/32894225
http://dx.doi.org/10.7554/eLife.58029

Ejemplares similares