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Size-dependent patterns of cell proliferation and migration in freely-expanding epithelia

The coordination of cell proliferation and migration in growing tissues is crucial in development and regeneration but remains poorly understood. Here, we find that, while expanding with an edge speed independent of initial conditions, millimeter-scale epithelial monolayers exhibit internal patterns...

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Detalles Bibliográficos
Autores principales: Heinrich, Matthew A, Alert, Ricard, LaChance, Julienne M, Zajdel, Tom J, Košmrlj, Andrej, Cohen, Daniel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498264/
https://www.ncbi.nlm.nih.gov/pubmed/32812871
http://dx.doi.org/10.7554/eLife.58945