MAPK activity dynamics regulate non-cell autonomous effects of oncogene expression

A large fraction of human cancers contain genetic alterations within the Mitogen Activated Protein Kinase (MAPK) signaling network that promote unpredictable phenotypes. Previous studies have shown that the temporal patterns of MAPK activity (i.e. signaling dynamics) differentially regulate cell beh...

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Detalles Bibliográficos
Autores principales: Aikin, Timothy J, Peterson, Amy F, Pokrass, Michael J, Clark, Helen R, Regot, Sergi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498266/
https://www.ncbi.nlm.nih.gov/pubmed/32940599
http://dx.doi.org/10.7554/eLife.60541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498266/
https://www.ncbi.nlm.nih.gov/pubmed/32940599
http://dx.doi.org/10.7554/eLife.60541

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