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Possible mechanisms of action of clarithromycin and its clinical application as a repurposing drug for treating multiple myeloma

Clarithromycin (CAM), a semisynthetic macrolide antibiotic, is a widely used antibacterial drug. Recently, the efficacy of CAM as an add-on drug for treating multiple myeloma (MM) has been noted. Its effect on treating MM has been confirmed in combination chemotherapies that include CAM. However, a...

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Detalles Bibliográficos
Autores principales: Takemori, Nobuo, Ooi, Hong-Kean, Imai, Goro, Hoshino, Kazuo, Saio, Masanao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498274/
https://www.ncbi.nlm.nih.gov/pubmed/33014130
http://dx.doi.org/10.3332/ecancer.2020.1088