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Predictions and analyses of RNA nearest neighbor parameters for modified nucleotides
The most popular RNA secondary structure prediction programs utilize free energy (ΔG°(37)) minimization and rely upon thermodynamic parameters from the nearest neighbor (NN) model. Experimental parameters are derived from a series of optical melting experiments; however, acquiring enough melt data t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498315/ https://www.ncbi.nlm.nih.gov/pubmed/32810273 http://dx.doi.org/10.1093/nar/gkaa654 |