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Predictions and analyses of RNA nearest neighbor parameters for modified nucleotides

The most popular RNA secondary structure prediction programs utilize free energy (ΔG°(37)) minimization and rely upon thermodynamic parameters from the nearest neighbor (NN) model. Experimental parameters are derived from a series of optical melting experiments; however, acquiring enough melt data t...

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Detalles Bibliográficos
Autores principales:	Hopfinger, Melissa C, Kirkpatrick, Charles C, Znosko, Brent M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Computational Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498315/ https://www.ncbi.nlm.nih.gov/pubmed/32810273 http://dx.doi.org/10.1093/nar/gkaa654

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