Cargando…

GapR binds DNA through dynamic opening of its tetrameric interface

GapR is a nucleoid-associated protein that is an essential regulator of chromosome replication in the cell cycle model Caulobacter crescentus. Here, we demonstrate that free GapR is a homotetramer, but not a dimer as previously reported (Guo et al., Cell 175: 583–597, 2018). We have determined the c...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Qian, Duan, Bo, Dong, Xianzhi, Fan, Shilong, Xia, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498317/
https://www.ncbi.nlm.nih.gov/pubmed/32756896
http://dx.doi.org/10.1093/nar/gkaa644