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GapR binds DNA through dynamic opening of its tetrameric interface
GapR is a nucleoid-associated protein that is an essential regulator of chromosome replication in the cell cycle model Caulobacter crescentus. Here, we demonstrate that free GapR is a homotetramer, but not a dimer as previously reported (Guo et al., Cell 175: 583–597, 2018). We have determined the c...
Autores principales: | Huang, Qian, Duan, Bo, Dong, Xianzhi, Fan, Shilong, Xia, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498317/ https://www.ncbi.nlm.nih.gov/pubmed/32756896 http://dx.doi.org/10.1093/nar/gkaa644 |
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