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NRF2 preserves genomic integrity by facilitating ATR activation and G2 cell cycle arrest
Nuclear factor erythroid 2-related factor 2 (NRF2) is a well-characterized transcription factor that protects cells against oxidative and electrophilic stresses. Emerging evidence has suggested that NRF2 protects cells against DNA damage by mechanisms other than antioxidation, yet the mechanism rema...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498319/ https://www.ncbi.nlm.nih.gov/pubmed/32729622 http://dx.doi.org/10.1093/nar/gkaa631 |