Cargando…

Tumor suppressor p53: from engaging DNA to target gene regulation

The p53 transcription factor confers its potent tumor suppressor functions primarily through the regulation of a large network of target genes. The recent explosion of next generation sequencing protocols has enabled the study of the p53 gene regulatory network (GRN) and underlying mechanisms at an...

Descripción completa

Detalles Bibliográficos
Autores principales: Sammons, Morgan A, Nguyen, Thuy-Ai T, McDade, Simon S, Fischer, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498329/
https://www.ncbi.nlm.nih.gov/pubmed/32797160
http://dx.doi.org/10.1093/nar/gkaa666