METTL4 catalyzes m(6)Am methylation in U2 snRNA to regulate pre-mRNA splicing

N (6)-methylation of 2′-O-methyladenosine (Am) in RNA occurs in eukaryotic cells to generate N(6),2′-O-dimethyladenosine (m(6)Am). Identification of the methyltransferase responsible for m(6)Am catalysis has accelerated studies on the function of m(6)Am in RNA processing. While m(6)Am is generally f...

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Detalles Bibliográficos
Autores principales: Goh, Yeek Teck, Koh, Casslynn W Q, Sim, Donald Yuhui, Roca, Xavier, Goh, W S Sho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498333/
https://www.ncbi.nlm.nih.gov/pubmed/32813009
http://dx.doi.org/10.1093/nar/gkaa684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498333/
https://www.ncbi.nlm.nih.gov/pubmed/32813009
http://dx.doi.org/10.1093/nar/gkaa684

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