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IMPLICON: an ultra-deep sequencing method to uncover DNA methylation at imprinted regions
Genomic imprinting is an epigenetic phenomenon leading to parental allele-specific expression. Dosage of imprinted genes is crucial for normal development and its dysregulation accounts for several human disorders. This unusual expression pattern is mostly dictated by differences in DNA methylation...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498334/ https://www.ncbi.nlm.nih.gov/pubmed/32621604 http://dx.doi.org/10.1093/nar/gkaa567 |