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IMPLICON: an ultra-deep sequencing method to uncover DNA methylation at imprinted regions

Genomic imprinting is an epigenetic phenomenon leading to parental allele-specific expression. Dosage of imprinted genes is crucial for normal development and its dysregulation accounts for several human disorders. This unusual expression pattern is mostly dictated by differences in DNA methylation...

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Detalles Bibliográficos
Autores principales: Klobučar, Tajda, Kreibich, Elisa, Krueger, Felix, Arez, Maria, Pólvora-Brandão, Duarte, von Meyenn, Ferdinand, da Rocha, Simão Teixeira, Eckersley-Maslin, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498334/
https://www.ncbi.nlm.nih.gov/pubmed/32621604
http://dx.doi.org/10.1093/nar/gkaa567