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Single-molecule fluorescence studies on cotranscriptional G-quadruplex formation coupled with R-loop formation
G-quadruplex (GQ) is formed at various regions of DNA, including telomeres of chromosomes and regulatory regions of oncogenes. Since GQ is important in both gene regulation and genome instability, the biological and medical implications of this abnormal DNA structure have been intensively studied. I...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498336/ https://www.ncbi.nlm.nih.gov/pubmed/32810236 http://dx.doi.org/10.1093/nar/gkaa695 |