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Single-molecule fluorescence studies on cotranscriptional G-quadruplex formation coupled with R-loop formation

G-quadruplex (GQ) is formed at various regions of DNA, including telomeres of chromosomes and regulatory regions of oncogenes. Since GQ is important in both gene regulation and genome instability, the biological and medical implications of this abnormal DNA structure have been intensively studied. I...

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Detalles Bibliográficos
Autores principales: Lim, Gunhyoung, Hohng, Sungchul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498336/
https://www.ncbi.nlm.nih.gov/pubmed/32810236
http://dx.doi.org/10.1093/nar/gkaa695