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Exploring the effect of nsSNPs in human YPEL3 gene in cellular senescence

YPEL3 that induces cellular senescence in both normal and tumour cells of humans may show altered expression under the influence of incidental mutations. In this study, we proposed the first structure of Native YPEL3 protein and its five possible deleterious mutants—V40M, C61Y, G98R, G108S, and A131...

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Detalles Bibliográficos
Autores principales: Singh, Abhishek, Thakur, Mukesh, Singh, Sujeet Kumar, Sharma, Lalit Kumar, Chandra, Kailash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498449/
https://www.ncbi.nlm.nih.gov/pubmed/32943700
http://dx.doi.org/10.1038/s41598-020-72333-8