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Wnt/β-catenin signaling pathway induces autophagy-mediated temozolomide-resistance in human glioblastoma

Temozolomide (TMZ) is widely used for treating glioblastoma multiforme (GBM), however, the treatment of such brain tumors remains a challenge due to the development of resistance. Increasing studies have found that TMZ treatment could induce autophagy that may link to therapeutic resistance in GBM,...

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Detalles Bibliográficos
Autores principales: Yun, Eun-Jin, Kim, Sangwoo, Hsieh, Jer-Tsong, Baek, Seung Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498596/
https://www.ncbi.nlm.nih.gov/pubmed/32943609
http://dx.doi.org/10.1038/s41419-020-02988-8