Ouabain-Induced Cell Death and Survival. Role of α1-Na,K-ATPase-Mediated Signaling and [Na(+)](i)/[K(+)](i)-Dependent Gene Expression

Ouabain is of cardiotonic steroids (CTS) family that is plant-derived compounds and is known for many years as therapeutic and cytotoxic agents. They are specific inhibitors of Na,K-ATPase, the enzyme, which pumps Na(+) and K(+) across plasma membrane of animal cells. Treatment of cells by CTS affec...

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Detalles Bibliográficos
Autores principales: Lopina, Olga Dmitrievna, Tverskoi, Artem Mikhaylovich, Klimanova, Elizaveta Andreevna, Sidorenko, Svetlana Vadimovna, Orlov, Sergei Nikolaevich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498651/
https://www.ncbi.nlm.nih.gov/pubmed/33013454
http://dx.doi.org/10.3389/fphys.2020.01060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498651/
https://www.ncbi.nlm.nih.gov/pubmed/33013454
http://dx.doi.org/10.3389/fphys.2020.01060

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