Neutral Sphingomyelinase-2 (NSM 2) Controls T Cell Metabolic Homeostasis and Reprogramming During Activation

Neutral sphingomyelinase-2 (NSM2) is a member of a superfamily of enzymes responsible for conversion of sphingomyelin into phosphocholine and ceramide at the cytosolic leaflet of the plasma membrane. Upon specific ablation of NSM2, T cells proved to be hyper-responsive to CD3/CD28 co-stimulation, in...

Descripción completa

Detalles Bibliográficos
Autores principales: De Lira, Maria Nathalia, Raman, Sudha Janaki, Schulze, Almut, Schneider-Schaulies, Sibylle, Avota, Elita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498697/
https://www.ncbi.nlm.nih.gov/pubmed/33088808
http://dx.doi.org/10.3389/fmolb.2020.00217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498697/
https://www.ncbi.nlm.nih.gov/pubmed/33088808
http://dx.doi.org/10.3389/fmolb.2020.00217

Ejemplares similares