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The Estradiol Synthesis Inhibitor Formestane Diminishes the Ability of Sevoflurane to Induce Neurodevelopmental Abnormalities in Male Rats

BACKGROUND: In rodents, the period of increased vulnerability to the developmental effects of general anesthetics coincides with the period of age-specific organizing (masculinizing) effects of the major female sex hormone 17β-estradiol (E2) in the male brain and excitatory GABA type A receptor (GAB...

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Detalles Bibliográficos
Autores principales: Wang, Jie, Yang, Baofeng, Ju, Lingsha, Yang, Jiaojiao, Allen, Andrea, Zhang, Jiaqiang, Martynyuk, Anatoly E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498728/
https://www.ncbi.nlm.nih.gov/pubmed/33013333
http://dx.doi.org/10.3389/fnsys.2020.546531